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Kendzerska T, Gershon AS, Hawker G, Tomlinson G, Leung RS

Current perioperative decisions should be individualized according to drug type, dose-escalation phase, gastrointestinal symptoms, aspiration risk, and surgical urgency, rather than managed by a single universal rule ( Long-term use and discontinuation also need to be considered

Eleven out of fourteen athletes developed patellar tendonitis in a short amount of time

Moreover, they have enabled real-time monitoring of resistance evolution and informed the development of personalized treatment strategies, including biomarker-guided therapy, adaptive dosing, and drug rechallenge protocols

As its use becomes more widespread, perioperative physicians and head-neck surgeons must be familiar with its pharmacokinetics and associated risks