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The present study brings some light into the understanding of the clinical, biochemical and immunological effect of zinc and selenium supplementation in clinically stable long-term treated PLWHIV without metabolic diseases or active coinfections
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In vivo, it has been observed that xenografts tumors are more resistant to FK866 treatment when NAPRT is upregulated, while they became more chemosensitive when NAPRT is silenced or inhibited
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