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Key Takeaways Semaglutide is a GLP-1 medication that helps reduce appetite and improve satiety Clinical trials show average weight loss of approximately 15 to 17 percent over 68 weeks Dosing is gradual to improve tolerance and reduce side effects Best results occur when combined with nutrition and clinical supervision Not appropriate for patients with certain thyroid conditions or MEN 2 Introduction Semaglutide is one of the most widely studied medications for weight management today

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doi: 10.31557/APJCP.2020.21.4.867