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[39] In animals, sodium valproate raises cerebral and cerebellar levels of GABA, possibly by inhibiting GABA degradative enzymes, such as GABA transaminase, succinate-semialdehyde dehydrogenase and by inhibiting the re-uptake of GABA by neuronal cells
Squalane can be derived from both plants and animals
In Phase 2 trials, nausea affected 28% of patients at the 12mg dose, peaking at weeks 6-8 and substantially resolving by week 12
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