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(Science-Based Medicine) Potential thyroid, kidney or metabolic disturbances some anecdotal reports and reviews raise these as possible but under-studied risks
Risk factors for SIBO include hypochlorhydria, motility disorders, irritable bowel syndrome, and medications such as proton pump inhibitors and histamine 2-receptor blockers
Tetrahedron Lett 39 , 74837486 (1998)
Further, UA or subsequently formed radicals can activate NADPH oxidase-dependent signaling pathways, causing oxidative stress and further activation of inflammatory processes in adipose tissue
Zheng L, Zhang Z, Sheng P, Mobasheri A
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