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doi: 10.1159/000341454 37 LiN.ZhaoY.YueY.ChenL.YaoZ.NiuW

Recent advances in Nrf2 activators, such as synthetic triterpenoids and natural compounds, highlight the need for temporal precisionactivating Nrf2 early to preserve -cell function but avoiding chronic overexpression, which may promote cancer (Mohamadi et al., 2023)

However, rapid weight loss can shift thyroid hormone metabolism and metabolism rate, potentially requiring levothyroxine dose adjustments

Vomiting Nausea and vomiting are common with retatrutide

Almost 7% of study participants permanently stopped taking the pill because of adverse effects, compared to almost 6% with a placebo