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Intranasal delivery offers a potential advantage: absorption through the olfactory and nasal mucosal pathways provides a more direct CNS route that partially bypasses the plasma degradation problem

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They are a great option for those who suffer from a vitamin B12 deficiency or just want to improve their overall health, especially in those who are unable to consume enough vitamin B12 through diet alone or who wish to experience the benefits much more efficiently as intravenous vitamins ensure that the entirety of what is injected into the body is able to be used, unlike consuming vitamins which are not 100% absorbed into the body

It's the mechanism

Drug Des, Dev Ther