ASC is produced by the terminal enzyme L-galactono-1,4-lactone dehydrogenase (GalLDH) also attached to the inner membrane and located in the mitochondrial complex I, and its presence is required for the stability of the complex (Pineau et al., 2008)
Thus, measuring the activity of this enzyme is an indicator of oxidative stress
The cells are packed with keratin and coated with lipids, forming a waterproof protective barrier
CrossRef Study Protocol of Multicenter Prospective Cohort Study of Active Surveillance on Papillary Thyroid Microcarcinoma (MAeSTro) Jae Hoon Moon, Ji-hoon Kim, Eun Kyung Lee, Kyu Eun Lee, Sung Hye Kong, Yeo Koon Kim, Woo-jin Jung, Chang Yoon Lee, Roh-Eul Yoo, Yul Hwangbo, Young Shin Song, Min Joo Kim, Sun Wook Cho, Su-jin Kim, Eun Jae Jung, June Young Choi, Chang Hwan Ryu, You Jin Lee Endocrinology and Metabolism.2018
Metabolic syndrome is a condition characterized by the presence of abdominal obesity, insulin resistance, hypertension, dyslipidemia, and glucose intolerance