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Combination potential: GLP-1 medications can be combined with SGLT2 inhibitors (another class with kidney benefits) for potentially additive protection

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Homocysteine is a thiol-containing amino acid, which suffers two major metabolic fates: remethylation catalyzed by methionine synthase (MS), methylenetetrahydrofolate reductase (MTHFR) or betaine-homocysteine methyltransferases (BHMT) and transsulfuration catalyzed by cystathionine -synthase (CBS) leading to cystathionine [3] (Figure 1)

For individuals with significant weight management needs, tirzepatide offers a highly effective solution