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6 Over the next few years, the teams at MGH and University of Copenhagen independently tested the effects of supplemental GLP-1 in people and found that infusing its biologically active form stimulated insulin secretion and lowered blood glucose

Many people choose to supplement alongside a healthy diet to bridge the gap and support their cellular health more robustly.

Stay hydrated with water, clear broths, or electrolyte drinks

However, this strategy is anecdotal and has not been formally studied in clinical trials, and individual responses vary considerably

Researchers at the Scandinavian Journal of Primary Health Care in 2025 found that GLP-1 users felt fuller and satisfied after their meals and that they had an easier time managing cravings