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You cannot run a binding assay on a compound with no known receptor Most of this catalogue is receptor pharmacology
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Extracapsular lens extraction with IOL implantation relies on the exceptional stability of the lens capsule compared to other basement membranes (which typically fully turn over every few days or weeks) as the removal of the lens fiber mass and molecular changes in the LECs presumably disrupt the normal processes ensuring lens capsule health (320, 321)
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