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Count data are presented as the rate or composition ratio using the chi-square test

Monitor urine color and frequency

To further elucidate the therapeutic mechanisms underlying D-CuPs multivalent interactions, comprehensive proteomic analysis revealed two pivotal transcriptional regulators, the tumor suppressor protein p53 and histone deacetylase 7 (HDAC7) to be potential mechanistic targets

Its primary mode of action is as a mu-opioid receptor agonist, meaning it binds to the same kind of receptors that morphine acts upon in the brain and spinal cord