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Recommended monitoring schedule Most thyroid specialists recommend: Testing thyroid function before starting Wegovy Follow-up testing after 3 months of treatment Additional testing after losing 10% or more of your body weight Regular monitoring as recommended by your doctor Signs your thyroid medication may need adjustment If you experience any of these symptoms while taking Wegovy, talk to your doctor, as they might mean your thyroid medication needs adjusting: Fast heart rate or feeling your heart racing Feeling anxious, irritable, or nervous Excessive sweating or feeling too hot Trouble sleeping Shaky hands or fingers Key points: Wegovy may slightly lower TSH levels, but this effect is usually mild As you lose weight, you may need less thyroid medication Regular thyroid function testing is important, especially after significant weight loss Watch for signs that your thyroid medication might need adjusting Important safety considerations When taking Wegovy with hypothyroidism, be aware of these important distinctions and considerations: Thyroid cancer risk vs

A schematic diagram detailing group assignments and experimental procedures is provided in Additional File 1: Figure S1

This preserves muscle mass during weight loss, which protects your metabolic rate and produces better body composition outcomes