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It is also a common reason for drugs to be withdrawn from the market

Understanding what to expect and how to respond makes the difference between a rough first few weeks and an unnecessarily miserable experience

doi: 10.4048/jbc.2023.26.e45

Bose A, Burman DR, Sikdar B, Patra P

Cleavage of SDF-1 by DPP-4 results in loss of activity (65), and consistent with this, DPP-4 inhibition in humans has been associated with enhancement of some effects which are associated with SDF-1 [increased levels of circulating endothelial progenitor cells (66) and increased distal tube sodium excretion (64)]