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Interestingly, CBS is upregulated by transcription factors such as nuclear factor erythroid 2-related factor 2 (NRF2) 17 , SP1/3 18 , and NFY 18 and its upregulation confers resistance against ferroptosis in ovarian cancer cells 17
The glycolytic enzyme PFKFB3/phosphofructokinase regulates autophagy
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These cells are glued together by proteins called Tight Junctions. When you eat a poor diet, take antibiotics, or live under chronic stress, this glue breaks down
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