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Aim : The aim of this study was to investigate the effect of UA on expression of antioxidant defense related enzymes in cultured J744A.1 macrophage cell line
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However, follow-up studies indicate that nearly 10% of individuals treated with ESAs develop resistance, a condition often linked to iron deficiency and systemic inflammation (van der Putten et al., 2008
To assess the utility of the model in a real world setting, we applied the model to a set of EHR data not used during model construction, and predicted efficacy at 6 months, assuming that the drug type and final dose was unknown at time point zero
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