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Animal species such as the mouse that are resistant to aflatoxin carcinogenesis have 3-5 times more GST activity than susceptible species such as the rat
Khounganian, R
Within 90 minutes of ingestion, cellular glutathione levels were seen to substantially increase reaching maximum levels after two to three hours, before returning to basal levels by five to 6 hours
We next performed a structural similarity search across our in-house compound collection, as well as on commercial small-molecule libraries (1,000,000 compounds) and identified 141 additional hits, which were screened in the high-throughput activity assay at a single concentration of 10 M
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