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For the long-acting injectables, because they are administered subcutaneously (under the skin) rather than orally, they bypass the gastrointestinal absorption process that can be influenced by stomach contents

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This makes it suitable for people with sensitive skin or inflammatory skin conditions such as eczema or rosacea

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Patients with genetic profiles indicating heightened GLP-1 sensitivity may achieve weight loss results at lower doses, potentially reducing the risk of rapid metabolic shifts that could destabilize mood