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Real needle-free GLP-1 exists: the Wegovy oral tablet (oral semaglutide 25 mg, FDA-approved December 2025, 13.6% weight loss in the OASIS 4 trial) and experimental microneedle patches from Daewoong Therapeutics (80% bioavailability in a 70-person Phase 1 study, 2028-2030 market estimate)
These lasting impacts have profoundly altered the lives of those who were meant to be helped
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This dual action not only improves diabetes control but can also lead to significant weight loss, which indirectly affects overall health, including sexual health
Observational data from the Osteoporotic Fracture in Men (MrOS) study suggested that men with T2DM treated with metformin showed slower loss of muscle mass measured by DXA over time than those not treated with insulin-sensitising agents [102]
