In line with evidence accrued in patients with T2D, incretin-based therapies produced a favorable effect on traditional cardiovascular risk factors, such as lipids and blood pressure, and even reduced the risk of major cardiovascular events and heart failure-related events in individuals with obesity, as recently demonstrated for the first time in the SELECT trial with semaglutide 2.4 mg once-weekly
Extreme sun exposure without protection, over-exfoliation, strong cleansers, and active chemical usage can all damage it
Laiteerapong N, Ham SA, Gao Y, et al
Nevertheless, several follow-up studies have reaffirmed DHODHs ferroptosissuppressive function under specific metabolic or oxidativestress conditions 93,94,95,96 , supporting the notion of a contextdependent mechanism rather than a universally essential role
22 (4), e20240134