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These compounds are frequently studied within the same broader research domain of growth hormonelinked metabolic signaling, but they operate at different levels of the pathway

While preliminary safety data appears promising, more comprehensive human studies are needed to establish definitive dosing guidelines and safety parameters

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Because a large number of comparisons were performed on the relative abundance data, main effect results from these analyses also underwent a BenjaminiHochberg false discovery rate (FDR) correction for multiple comparisons, and instances where a result was significant after this correction have been duly noted

Hence, it was not until 2009 when a harmonised definition was finally described [2]