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While the protection of normal cells against radiation-induced cell death by ebselen has been attributed to its ability to detoxify cellular/mitochondrial ROS through the GPx mechanism, the molecular mechanism contributing to its radio-sensitization effect in cancer cells is still not fully understood

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In preclinical research, AOD9604 is primarily investigated for its selective lipolytic activitythe ability to stimulate fat breakdown (lipolysis) and inhibit fat synthesis (lipogenesis) without exhibiting the growth-promoting or diabetogenic effects of full-length growth hormone