Cao, Y., Kamrani, E., Mirzaei, S., Khandakar, A
Learn more about vitamin B12 deficiencies
ICH Q3A(R2) describes general impurity categories for chemically synthesized substances, and ICH Q3C(R9) describes the control of residual solvents
Despite promising preclinical data, clinical trials in humans are extremely limited, and the compound remains largely experimental, with ongoing research required to fully characterize pharmacokinetics, optimal dosing, long-term safety, and potential off-target effects
Elastin fibers are damaged and have limited capacity to regenerate naturally (adult humans produce very little new elastin after puberty under normal conditions)