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Serum IGF-I measurement Serum IGF-I was measured centrally at qLAB (Livingston, Edinburgh, UK) using the DCP chemiluminescent immunoassay (Immulite 2000, Siemens Healthcare Diagnostics , Norwood, MA, USA)

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Only two studies to date have reported dual inhibitory compounds, specifically compounds 84 (Zinc41306568) and 87 90