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Continuous use without breaks is not recommended
A subsequent larger RCT (n=72) confirmed these findings, showing improvements in gait speed, grip strength, exercise capacity, waist circumference, and systolic blood pressure (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]
However, phase II clinical trials were conducted to investigate ipamorelin for post-operative ileus treatment but the trials were discontinued due to its limited efficacy
Preclinical rodent studies most commonly use 100300mcg/kg body weight per injection once daily, with 200mcg/kg being the most frequently replicated dose in peer-reviewed GH secretion studies
Pruseth et al
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