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In animal reproduction studies, congenital abnormalities were observed in fetuses of pregnant rats but not in fetuses of pregnant rabbits exposed during organogenesis to pramlintide at 10 times the clinical dose of 360 mcg/day, based on exposure (see Data)
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When the pre-grown cells were further used for biotransformation, the highest l-DOPA yield was 0.61 0.02 g/gDCW with 4 mM ascorbic acid
FUS-BBB opening alone did not have a noticeable effect on GSK-3 activity in cortex nor hippocampus compared to the control group
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