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The first four categories are the highest-priority avoidances
The tolerability story is also good: nausea rates of 25% are lower than Semaglutides, which aligns with the theory that GIP co-activation improves GI tolerance
This means it works by mimicking a natural hormone in the body that helps control appetite
This is why lyophilized (freeze-dried) powder is inherently more stable than a pre-mixed solution: removing water removes the hydrolysis substrate
GLP-1 is an incretin hormone that is produced and secreted by intestinal L-cells and in the central nervous system by neurons in the brainstem
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