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The tendency for some individuals to have received DPP-4is before switching to GLP-1 RAs may account for the longer diabetes duration and the slightly higher prevalence of diabetic complications and hypertension in the GLP-1 RA group
Even patients who weren't at goal on another GLP-1 agonist have seen additional weight loss and blood sugar control when switching to tirzepatide
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HE and MT (for collagen fiber) staining showed destruction of the normal pancreatic structure, as well as fibrosis in peri-islet-areas (P-IAs) and stromal fibrotic areas (FAs
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