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PIONEER 3 PIONEER 3 compared the efficacy and safety of the addition of oral semaglutide or the DPP-4 inhibitor sitagliptin as add-on therapy in patients with T2DM receiving metformin with or without a sulfonylurea

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Calculating solute permeabilities and comparison to experimental measurements The permeability P of a solute diffusing through a membrane patch of area S can be obtained from the transport rate r observed in a simulation using: where C is the solute concentration in the aqueous phase (see Supporting Material for details)