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Our results confirmed that the reduction of APAP concentration in blood observed over time in intoxicated patients was always associated with an increase in thiomethyl metabolites signals (mainly as S-CH 3 -APAP-S as observed in the intervention study) (Fig
2h, Supplementary Fig
doi: 10.1113/jphysiol.1970.sp009155 11 DupreJRossSAWatsonDBrownJC
& Mattie, M
In addition, the incubation the neuron cell lines with LLP-1 induced a decrease in GSH levels, mitochondrial membrane depolarization, and H 2 O 2 production rapidly
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