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What changed is that subcutaneous absorption from the injection depot is now slower than elimination, so absorption rather than clearance governs the observed curve a phenomenon pharmacologists call flip-flop kinetics

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[Platelet glutathione reductase and glutathione-S-transferase in elderly research [PMID: 34693693] Laboratory literature summary: [Platelet glutathione reductase and glutathione-S-transferase in elderly research subjects with depression]

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Data integration Following quality control, we normalized the raw counts with the NormalizeData function in Seurat (17), producing a log-normalized count matrix for downstream analyses