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Pro-oxidants: fresh hydrogen peroxide (Sigma, UK) solution was prepared as a 10 mM stock solution immediately before use then diluted to the required concentration
water-soluble by nature, involved in formation of red blood cells, strengthening nervous system, maintaining metabolism etc
A simple way to avoid the issue is to take creatine with food, avoid loading phases, or take multiple smaller doses (3-5 grams) during a loading phase
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The therapy also improved cardiovascular risk factors despite a 20.8% discontinuation rate due to gastrointestinal side effects
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