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Ten-eleven Translocation (TET) enzymes converts methylcytosine (m 5 C) to hydroxymethylcytosine (hmC), which is not recognized by Dnmt1, it is believed to exclude maintenance methylation allowing for passive demethylation, and it is an intermediate in the active conversion of m 5 C to cytosine (C) 27
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For patients with Long COVID or ME/CFS, practitioners often recommend starting with a smaller dose (e.g., 1/4 or 1/2 scoop) to assess tolerance, as rapid detoxification can sometimes cause a temporary exacerbation of symptoms (a Herxheimer reaction) as toxins are mobilized
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