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Fasted: Taking L-Carnitine on an empty stomach might be preferable for those looking to maximize fat burning during exercise, as it may increase the availability of L-Carnitine for fat oxidation
J.AtkinsonC.BhallaK.BirbeckG.BursteinR.ChouD.et al (2013)
This assertion is backed by some early animal research
AOD 9604 best clinical result was approximately 2.8kg of additional fat loss over 12 weeks, and the larger confirmatory trial (OPTIONS study, 536 subjects, 24 weeks) failed to show statistically significant weight loss compared to placebo
Methods Cell Biol 2007
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