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262,263 Hypogonadotropic hypogonadism is a condition marked by levels of gonadotropins (LH and FSH) that are too low to support normal ovarian function
Trial-Reported Endpoints by Phase Trial Lancet 2021 Phase 2 Duration 26 weeks Population Overweight/obese, no T2D (n=706) Mean Weight Loss 10.8% at 4.5 mg vs 3.0% placebo Trial Lancet 2023 Phase 2 Duration 32 weeks Population T2D + obesity (n=92) Mean Weight Loss 8.1% cagrilintide alone
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The more MTHFR gene mutations you have, the less the MTHFR enzyme can do its job effectively
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