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10.1016/j.ijcard.2012.09.058 93
Abstract Nicotinamide adenine dinucleotide (NAD + ) is an essential molecule involved in cellular metabolism, and its decline has been implicated in ageing and age-related disorders
This TYR-catalyzed PROTAC design facilitates the in-situ cross-linking of two small molecules for targeted protein elimination, bypassing the need for prior covalent conjugation and mitigating issues of large molecular weights and unfavorable pharmacological properties of traditional PROTAC design
10.1038/s41598-017-18278-x 77 LiT.FanG
PubMed 13
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