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Normally microglia are neuroprotective, cleaning out debris that may contribute to neurodegenerative diseases or damage from ischemic stroke, but in the case of TBI they can become overactivated and exacerbate neuroinflammation (with upregulated TNFa, IL-6, C3, NK-kB, CD68, etc), and vascular changes can result in headaches, neurovascular flow changes, impaired lymphatic flow, blood-brain barrier disruption, activation of pro-inflammatory pathways, neuronal death, hyperexcitability, and disrupted synaptic connections
NAD+ IV Therapy: Supports cellular repair and sustained vitality
doi: 10.3390/nu10091199 26
Important points Dont take more medication than the dose prescribed
Unlike GLP-1 agonists, it preserves lean muscle mass during caloric restriction
