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Our search strategy included both free-text and Medical Subject Headings (MeSH) terms, utilising the keywords tirzepatide, ly3298176, semaglutide and nn9535 (electronic supplementary material [ESM] Table 1)

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Inactive ingredients: Dibasic sodium phosphate dihydrate Propylene glycol Phenol Hydrochloric acid Sodium hydroxide Water for injections Each pen contains 2 mg semaglutide , allowing for 0.25 mg or 0.5 mg dose selections