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Science 272 , 11361144 (1996)

Glutathione works by inhibiting tyrosinase, an enzyme involved in melanin production, leading to a gradual brightening effect

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In these circumstances, the ability of ascorbic acid to substitute for GSH by redox and non-redox pathways is invaluable (30), as is heightened activity of gamma glutamyl transpeptidase (GT) in the plasma membrane, which enables the uptake of reconstituting amino acids from the plasma GSH pool (138, 170) - but these resources are finite

Dougnon G, Matsui H (2025) Lipofuscin accumulation in aging and neurodegeneration: a potential timebomb overlooked in Alzheimers disease