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The 2HG content of experimental samples was determined by interpolation using 2HG peak areas measured in the standards
Some studies have identified metabolic deficiencies in autistic children [14], and it has recently been shown that there is a characteristic metabolic profile in many autistic children involving disturbances in methionine and glutathione metabolism [14, 15]
Proc Natl Acad Sci U S A 109(51):2112821133 Schwechter B, Rosenmund C, Tolias KF (2013) RasGRF2 Rac-GEF activity couples NMDA receptor calcium flux to enhanced synaptic transmission
In string three we searched with the same initiation and adverse effects terms in conjunction with alternative words and phrases used to describe a KD or methods of initiating ketosis, for example: low-carbohydrate, fasting, starvation, carbohydrate restriction or low-calorie
Although exploratory, the analyses were methodologically sound, with consistent results across renal risk categories and objective outcome ascertainment, leading to an overall moderate risk of bias and moderate-certainty evidence
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