Additionally, certain GLP-1 agonists have shown efficacy in addressing obesity concerns
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[11] The research also suggests that magnesium status may influence the progression of hypertension, atherosclerosis, and kidney disease, which are common comorbidities of type 2 diabetes
The current understanding points to a potential biphasic pattern in GLP-1 RA studies, where any observed early worsening may be related to rapid glycemic improvement rather than direct retinal toxicity, particularly in patients with pre-existing retinopathy, poor glycemic control, and those undergoing HbA1c reduction 47