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Investor concern is that the company is losing market share to its US rival Eli Lilly, which makes the diabetes and obesity drugs Mounjaro and Zepbound
Depression, circadian phase advance, cortisol, medication withdrawal and metabolic changes may be relevant
Its FDA label has grown from a single T2D indication in 2017 to six approved indications by early 2026: type 2 diabetes, chronic weight management (injectable and oral), cardiovascular risk reduction, chronic kidney disease protection, and MASH
Additionally, wrinkle volume reductions of up to 55.8% have been measured in 12-week topical studies
Rare cases have involved serious heart valve problems and dangerously high blood pressure. Semaglutide side effects Semaglutide primarily affects the digestive system
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