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Many weight loss methods, including GLP-1 medications like semaglutide and retatrutide , lead to unintended loss of lean mass
The SURMOUNT-1 trial of tirzepatide showed a similar pattern, with greater absolute weight loss but the same shape: a steep early decline, a gradual deceleration, and a plateau that arrived later but arrived nonetheless
It is used for peripheral neuropathy (pain in nerves, usually in lower limbs and hands)
How are you able to tell when Semaglutide GLP-1 is working
While tirzepatide preserves lean mass better than diet alone, some researchers look for ways to further protect muscle during aggressive weight loss
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