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Transmission electron microscopy of Raji cells Untreated Raji cells, Raji cells treated with TPA for 24 h, Raji cells treated with TPA and 200 ng/ml TNF-, cells treated with 10 M erastin and 10 M Fer-1 sh-NC and sh-GPX4 cells were collected and fixed by the addition of electron microscope fixative (G1102 Servicebio) for 2 h at 4 C

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In addition to oncogenic regulators, there are some key upstream regulators of glutamine metabolism that are widely recognized for their pivotal role during tumorigenesis