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I only really hear about microdosing when it comes to compounding medications, which we never recommend, or off-label use of GLP-1s for longevity, addiction, and other indications. Although many doctors are writing prescriptions for GLP-1 microdosing, experts are concerned that they may not always be acting scrupulously, especially when working with less-reputable online compounding pharmacies
The simplicity of the procedure is precisely what creates risk in certain settings
That conversation is the responsible first step
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et al: GLP-1RA and SGLT2i Medications for Type 2 Diabetes and Alzheimer Disease and Related Dementias. JAMA Neurology, April 7, 2025
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