smart scripts tirzepatide Compounded — Dual GLP-1/GIP Weight Loss Medication What else does Smartscripts send?

| Risk Tier | Drug Class | Interaction Type | Management Action | |---|---|---|---| | Tier 1 (Act Before Prescribing) | Basal insulin, sulfonylurea | Additive hypoglycemia | Reduce co-medication dose 20-50% before first tirzepatide dose | | Tier 1 (Act Before Prescribing) | Oral contraceptives | Reduced Cmax 20-23% | Switch to non-oral method or add barrier for 4 weeks per escalation | | Tier 2 (Monitor Within 4-8 Weeks) | Levothyroxine | Absorption rate change | Recheck TSH at 6-8 weeks and after each dose escalation | | Tier 2 (Monitor Within 4-8 Weeks) | Warfarin | Indirect INR shift via diet and motility | INR at 2-4 weeks after initiation | | Tier 2 (Monitor Within 4-8 Weeks) | ACE inhibitors, ARBs, thiazides | Relative overdose from weight-loss BP reduction | Blood pressure at every visit

Resistance training (including after lymph node surgery) Older guidance discouraged lifting weights after axillary surgery, but current evidence shows resistance training doesnt worsen lymphoedema and improves strength and shoulder function

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doi: 10.1161/CIRCULATIONAHA.117.028136 22 ChangWZhuFZhengHZhouZMiaoPZhaoLet al