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Day of the procedure: If gastrointestinal symptoms are present, including severe nausea/vomiting/retching, abdominal bloating, or abdominal pain, consider delaying the elective procedure and discuss the concerns of potential risk of regurgitation and pulmonary aspiration of gastric contents with the proceduralist/surgeon and the patient
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The paper appeared in Angewandte Chemie International Edition on March 12, 2026, with the formal title "Direct Selection of Functional De Novo Macrocycles for Activation of On-Cellulo Insulin Receptor." It carries the DOI 10.1002/anie.202526008, sits on PubMed at PMID 41815006, and was featured by the American Peptide Society on May 12, 2026 as "Function-First Macrocycles"
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