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[11] Long-term metformin therapy reduces calcium-dependent intrinsic-factor binding, lowering B12 absorption and potentially necessitating higher or more frequent parenteral doses
Reconstituted solutions should be kept refrigerated at 2-8C rather than refrozen, and any single vial should not be subjected to more than one freeze-thaw event if freezing cannot be avoided
Krivic A, Anic T, Seiwerth S, Huljev D, Sikiric P
Getting NICE to produce a Guideline will mean that over a three to four year period NICE will consult with stakeholder groups, including ourselves, and thoroughly review the way in which Pernicious Anaemia is diagnosed and treated
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