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Conversely, acute stimulant exposure downregulates miR-495, relieving its suppression of BDNF and calcium/calmodulin-dependent protein kinase II alpha in NAc 115

The most important risk factor is concomitant use of insulin or insulin secretagogues (sulfonylureas such as glipizide, glyburide, or glimepiride, and meglitinides such as repaglinide)

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These often trigger nausea

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