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Originally used to treat type 2 diabetes, semaglutide caught the attention of doctors and researchers when patients started shedding serious pounds

The aggressive titration tail in the 12 mg arm of the Phase 2 trial was strongly associated with higher rates of transient gastrointestinal adverse events, which is why researchers generally favor slower escalation when tolerability is prioritized

The incidence of adverse reactions, including nausea, vomiting, and loss of appetite, in two groups was recorded

[50] Researchers have estimated that during the Age of Exploration (between 1500 and 1800), scurvy killed at least two million sailors